Welcome to

THE PANACEA MOTEL

The Coziest Place to Stay in Panacea, Florida

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You deserve a break by the beach

Relax and Unwind at The Panacea Motel – Your Gateway to Florida’s Hidden Gem

At The Panacea Motel, we provide a comfortable and inviting stay as you explore the charm of Florida’s Forgotten Coast.

Our rooms are equipped with everything you need for a relaxing retreat, including a cozy queen bed, a private trail leading to the bay,

flat-screen TV, a bathroom with complimentary toiletries, and convenient access to a microwave and fridge.

Each room features its own unique decor, all inspired by a fresh, coastal beach style. This creates the perfect atmosphere for you to unwind, de-stress, and enjoy the natural beauty of the beach just outside your door.

Find the best room for your vacation!

Larger Properties

Check out some of our other larger properties. These feature king beds and a larger space for you and your family. From our Hidden Gem to our Bungalow Cottage, we are sure to have something perfect for your travel occasion. They are sure to feel like a home away from home.

SEE OUR ROOMS⤑

Panacea Motel

This spot is great for staycations, romantic getaways, or a quick rest stop. Whether you are staying here for one night or one month, it is a central location for many attractions.

SEE OUR ROOMS ⤑

See What Our Guests are Saying About Us!

Alan L.

“Great little spot, very comfortable and decorated nicely. Short walk to the bay where we enjoyed a little fishing. Very accommodating for our pups.”

Alex P.

“I felt like I was one of the family! I love them. I would stay here again no doubt. Panacea is a little hidden gem with Mashes Beach a few minutes by car down the road.”

Jeffrey H.

“Loved that the kitchen was supplied with olive oil, red sea salt, peppermill other spices and nice pots and pans. They were very quick to reply anytime I contacted them.” 

Brent S.

“The cutest little place and very clean! Also loved the little walking trail out back down to the bay. Definitely coming back again soon! Hopefully for the blue crab festival”

Perfectly Located for Your Coastal Adventure


  • Wakulla Springs – Just 25 minutes away
  • St. George Island – Only 1 hour away
  • Apalachicola – A scenic 1-hour drive
  • Tallahassee – Conveniently located 40 minutes away


Explore the best of Florida’s Forgotten Coast, all within easy reach of The Panacea Motel.

 Unwind in Comfort, Your Way

We’re here to ensure you have an unforgettable stay.
If there’s anything you need or if we can assist you in any way, don’t hesitate to let us know.


Call us ⤑